2021 Symposium Topics:
- Gastrointestinal NETS
- Multiple NETs
- Pheochromocytoma and Paraganglioma
- Pancreatic NETs
SESSION 1: Gastrointestinal NETs
Presentations
- Rare Cancer Initiative Effort: A Roadmap For Neuroendocrine Tumor Dependency
 Moony (Yuen-Yi) Tseng, PhD, Broad Institute (Eli and Edythe L. Broad Institute of MIT and Harvard)
- Whole genome sequencing reveals the independent clonal origin of multifocal ileal neuroendocrine tumors
 Netta Mäkinen, PhD, Dana-Farber Cancer Institute
- Metabolomic Profile of Gastrointestinal and Pulmonary Neuroendocrine Tumors: Prognostic and Biological Relevance
 Anna La Salvia, MD, Hospital Universitario 12 de Octubre
- Nanobody-directed CAR T cells eliminate neuroendocrine tumors without toxicity via masking of the antigen target in normal cells
 Xianxin Hua, MD, PhD, University of Pennsylvania
SESSION 2: Multiple NETs
Presentations
- Biodistribution and radiation dosimetry of 68Ga-DOTA-JR11 in patients with metastatic neuroendocrine tumors
 Simone Krebs, MD, Memorial Sloan Kettering Cancer Center
- Multimodal analogs of DOTA-JR11 to investigate the unexpected bone marrow toxicity in NET patients
 Susanne Kossatz, PhD, Technical University Munich
- Engineering Decreased Nephrotoxicity for SSTR2 Targeted Alpha Therapy
 David Morse, PhD, H. Lee Moffitt Cancer Center & Research Institute
- uPAR-targeted PRRT: new radionuclide-based therapy
 Andreas Kjaer, MD, PhD, Copenhagen University Hospital (Rigshospitalet)
- Digital Image Analysis in Neuroendocrine Tumors
 Michelle Kim, MD, PhD, Icahn School of Medicine at Mount Sinai
- SV2A PET Imaging for Noninvasive Assessment of Neuroendocrine Differentiation in Neuroendocrine Tumors
 Guiyang Hao, PhD, UT Southwestern Medical Center
- SSTR2-targeted delivery of temozolomide
 Solmaz Aghaamiri, The University of Texas Health Science Center at Houston
SESSION 3: Pheo/Para & Lung NETs
Presentations
- Succinate accumulation is not sufficient for tumorigenesis in mouse chromaffin cells but dual loss of SDHB and NF1 yields SDHx-like pheochromocytomas
 Justin Annes, MD, PhD, Stanford University
- Adverse effects of oxygen in a cell culture model for SDHB-mutated Pheochromocytoma/Paraganglioma
 Arthur Tischler, MD, Tufts Medical Center
- First PET Imaging Studies with 3-[18F]fluoro-p-hydroxyphenethylguanidine ([18F]3F-PHPG) in Paraganglioma and Pheochromocytoma Patients
 David Raffel, MD, The Regents of the University of Michigan
- Organoid Models of Normal and Malignant Neuroendocrine Cells Reveal Pathways Important for Neuroendocrine Cell Growth, Differentiation, and Transformation
 Talya Dayton, PhD, Hubrecht Institute of Developmental Biology and Stem Cell Research
- Tumor xenografts in zebrafish: a new in vivo model for lung carcinoids
 Giovanni Vitale, MD, PhD, Istituto Auxologico Italiano
SESSION 4: Pancreas NETs
Presentations
- Patient-derived Islet-like Tumoroids reflect phenotypic landscape of original Pancreatic Neuroendocrine Neoplasms and facilitate in vitro drug screening
 Simon L. April-Monn, University of Bern (Universität Bern)
- RABL6A-Myc signaling promotes pancreatic neuroendocrine tumor cell proliferation and survival
 Ume Salma Shaik Amjad, PhD, The University of Iowa
- Loss of MEN1 function inhibits DNA repair capability of pancreatic neuroendocrine tumors
 Xavier Keutgen, MD, The University of Chicago
- Loss of Men1 and Pten promotes invasion and metastasis of pancreatic neuroendocrine tumors
 Ziqiang Yuan, MD, Rutgers University Foundation
- The Importance of DDR genes in Response to PRRT- Evidence for PARP and DNA-PK as 
 Therapeutic Targets to Increase Efficacy
 Rodney Hicks, MD, Peter MacCallum Cancer Centre
- Angiopoietin-2/Tie2 signaling regulation of liver metastasis in pancreatic neuroendocrine tumors
 Minah Kim, PhD, Columbia University Medical Center
- The role of the B7x signaling pathway in the development and progression of neuroendocrine tumors
 Steven Libutti, MD, Rutgers, The State University of New Jersey
Date
November 17-18, 2020
Location
Norton’s Woods Conference Center
American Academy of Arts & Sciences
136 Irving St, Cambridge, MA 02138
 
								 
								 
								 
								 
								 
								 
								 
								 
								