Project title: Development of ex-vivo models of metastatic neuroendocrine tumors

Raj Srirajaskanthan, PhD Kings College London, United Kingdom

Raj Srirajaskanthan, PhD
  • Status: Completed
  • Year(s): 2018
  • Grant Type: Pilot
  • Research Type: Basic
  • Primary Tumor Site: Other
  • Area of Inquiry: Models

General Description

This Pilot Project aims to develop a laboratory model, whereby neuroendocrine tumors that have spread to the liver will be removed from the patient during surgery and successfully grown in the laboratory. Using precision cut slice technology, the investigators will cut and culture tissue slices from tumor and adjacent healthy tissue in conditions that will maintain their original tissue properties. They will then be able to use this tool to test responses to various drugs. The finding of this study might lead to translational research with the potential to enable the development of personalized medicine for treatment of NETs.


Additional Details

  • State: International
  • Grant Duration: 1 year
  • Awards: Pilot Project
  • Sponsor: Margie & Robert E. Petersen Foundation


NETRF funds laboratory research to understand the development of neuroendocrine tumors and translational research to explore new concepts in treatment. Research grant descriptions and research updates from NETRF are not intended to serve as medical advice. It can take years for research discoveries to be fully validated and approved for patient care. Always consult your health care providers about your treatment options.

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