Urine Tests for Neuroendocrine Tumors
Hydroxyindoleacetic acid (5-HIAA) urine test
Hydroxyindoleacetic acid (5-HIAA) is a breakdown product of the hormone serotonin. Neuroendocrine tumors can secrete this hormone. Since serotonin levels go up and down throughout a normal day, a 24-hour urine collection of the 5-HIAA byproduct is a more reliable measurement of daily amounts of the hormone. Your doctor may use the 5-HIAA test in diagnosing and monitoring neuroendocrine cancer.
Foods to avoid for 48 hours before a Hydroxyindoleacetic acid (5-HIAA) urine test:15
- Hickory nuts
- Honeydew melon
- Tomatoes and tomato products
There may also be prescription and over-the-counter medications to avoid before a 5-HIAA urine check. Make sure to get a complete list of foods and medications to avoid before the 5-HIAA test from your doctor.
Thor Halfdanarson, MD, Mayo ClinicNETs Overview Watch Video
Lowell Anthony, MD, University of KentuckyDiagnosis and treatment of NETs. Watch Video
Chrissie Thirlwell, MD, PhD, University College London Cancer InstituteTesting for NET biomarkers. Watch Video
Dan Halperin, MD, MD Anderson Cancer CenterUnderstanding tumor site, stage, and grade. Watch Video
15National Comprehensive Cancer Network® (NCCN). NCCN Guidelines Neuroendocrine and Adrenal Tumors. (Version 3.2018) https://www.nccn.org/professionals/physician_gls/PDF/neuroendocrine.pdf. Accessed October 24, 2018