Project title Researcher(s)

Unfolded protein response in NETs

Scott André Oakes, MD

Enlightenment of a new era of cancer therapy: prognostication, target selection, and subsequent therapy determined by the dual tumor-immune phenotype

Holbrook Kohrt, MD, PhD; Pamela Kunz, MD

Defining the immune landscape of NETs – towards rational combination therapy

Tim Meyer, MD, PhD

Molecular analysis of the immune environment of neuroendocrine tumors and associations with clinical outcomes

Matthew H. Kulke, MD

Developing novel treatments for NETs using CAR T-Cell Technology

Carl June, MD; Xianxin Hua, MD, PhD; David Metz, MD

Multifunctional nanomedicine for targeted carcinoid cancer therapy

Herbert Chen, MD

Implication of heterogeneous innate immune cells in pancreatic NET resistance

Gabriele Bergers, PhD

Identifying altered epigenetic states and drivers in intestinal carcinoid and pancreatic NETs

Bradley Bernstein, MD, PhD

Epigenomic analysis of intestinal neuroendocrine cells and the epigenetic basis of NETs

Ramesh Shivdasani, MD, PhD

Theranostics of NETs with somatostatin antagonists

Wolfgang Weber, MD, PhD; Diane Reidy-Lagunes, MD

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