Episode 4: Nuclear Medicine for NETs: What is PRRT?
Treating NETs with Nuclear Medicine
This episode of NETRF’s NETWise podcast discusses Peptide Receptor Radionuclide Therapy (PRRT) a targeted form of radiotherapy approved in the U.S. in 2018. Listen in as NET experts like Josh Mailman, Drs. George Fisher, Thor Halfdanarson, Ed Wolin, Richard Baum, and others explain what it is, how it works, and who is most likely to benefit from PRRT. This therapy relies on a tumor’s expression of somatostatin receptors. We explain what they are and how to know if you have them.
Then, we’ll take an objective look at the success rates for this therapy. What does research, like the NETTER-1 study, tell us about outcomes for this form of treatment? To give you information about both the pros and cons of PRRT, we will also discuss the potential side effects, from mild to serious. To give you a sense of what it is like to undergo PRRT, we’ll talk with multiple patients about their experience with the procedure itself, as well as the radiation safety precautions patients should take immediately following treatment. Finally, we look to the future asking Drs. Rod Hicks and Tom Hope to explain some of the new therapeutic directions PRRT is taking.
Use our episode infographics to get a visual picture of some of the things we have discussed.
PRRT for NETs. This handout explains how radioactive drugs are able to target NET cells with radioactivity using PRRT.
What is PRRT? A quick guide to answer your most basic questions about the pros and cons of PRRT. What are the benefits of PRRT? What are the potential side effects of PRRT? Who can be treated with PRRT?
Mentioned in this Episode:
Gallium-68 Dotatate PET/CT Scan
Search for PRRT treatment Centers Near You
VIDEO: How PRRT Works and Who Benefits – Dr. Blase Polite, University of Chicago
VIDEO: What to Expect During PRRT Treatment – Karen Ohara, Rush University Medical Center
VIDEO: How PRRT Can Improve Care for NET Patients
VIDEO: Combining PRRT with Targeted Therapy
VIDEO: Tb-161: Exploring a New Radionuclide for PRRT
Additional NET Research Foundation Resources:
Request a mailed copy of our Neuroendocrine Cancer Guide
Information and Resources for the Newly Diagnosed
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