Multipronged approaches to develop immunotherapy targeting NETs

Year: 2018
Institution: The Trustees of the University of Pennsylvania
Country: United States
State: PA
Award Type: 2018 Awards
NET Type: Pancreas
Science Type: Translational

General Description

By taking advantage of unique properties of NETs that are not found in healthy cells, researchers will try to target chemotherapy to attack only cancer cells, instead of all cells. Creating novel chemotherapeutic agents that will attack and kill only NET cells, will help reduce the side effects of currently used systemic chemotherapy.

Published PapersĀ 

Horton TM, Sundaram V, Hye-Jin Lee C, et al. PAM staining intensity of primary neuroendocrine neoplasms is a potential prognostic biomarker. Scientific Reports. 2020; (10):10943.