George Fisher, MD, PhD
Co-Chairman
Biography
I conduct clinical research on a variety of gastrointestinal cancers and provide care for patients with those cancers. We have trials of combined modality therapy (surgery +/- radiation +/- chemotherapy) on gastric, esophageal, pancreas and rectal cancers. We also perform phase I and II trials of biologically targeted agents as well as newer immunotherapeutics. In collaboration with a number of colleagues, we conduct translational studies analyzing novel imaging (e.g. contrast enhanced ultrasound and perfusion scans) and molecular biomarkers. Neuroendocrine tumors, pancreas, colorectal and gastro-esophageal cancers have been areas of particular research focus with multiple therapeutic and translational studies devote to each. Examples of recently completed trials include a randomized phase III trial of a vaccine (algenpantucel) for resected pancreas cancer, phase Ib trial of anti-PD-L1 and separate phase II trials using chemotherapy with angiogenesis inhibitors for advanced neuroendocrine tumors and gastro-esophageal adenocarcinomas. Currently active areas of study include combining immunomodulating antibodies against checkpoint inhibitors and a trial of an antibody to interleukin 1 for colorectal cancer. Participation and leadership in NCI cooperative group protocols gives our patients access to the randomized trials that hope to establish new standards of care for a variety of GI cancers.
Profession:
Professor of Medicine, Stanford University Cancer Center
Education:
Fellowship:Stanford University Medical Center (1993) CA
Residency:Stanford University Medical Center (1989) CA
Internship:Stanford University Medical Center (1988) CA
Medical Education:Stanford University School of Medicine (1987) CA
BS, Stanford University, Biology (1976)
PhD, Stanford University, Cancer Biology (1987)
MD, Stanford University, Medicine (1987)
Residency, Stanford University, Internal Medicine (1989)
Fellowship, Stanford University, Medical Oncology (1993)
External Biography
